Alicia Holk

Alicia Holk has been teaching biology and biomedical sciences since 2016. Before joining Harford Community College, she studied at the University of North Carolina, Chapel Hill, where she identified novel cancer antigens and developed drug discovery protocols later acquired by AstraZeneca. Alicia then worked at Analytical 360, conducting industrial quality testing on agricultural products and water safety. At Lovelace Biomedical Research Institute, she managed multi-million-dollar research trials, including COVID-19 studies from 2020 to 2021, and introduced 3D printing technology to create affordable, customizable consumables for BSL-3 research. Alicia's teaching connects traditional biological studies with modern technological applications and societal needs.

SCHOLARLY/CREATIVE WORK

PUBLICATIONS 

• Gao, Y., Mutter-Rottmayer, Holk, A., E., Goldfarb, D.,Yan, F., Tateishi, S., Major, B.M., Vaziri, C. (2016) A Neomorphic Cancer Cell-Specific Role of MAGE-A4 in Trans-Lesion Synthesis (TLS) Nat Commun. Jul 5; 7:12105 
• Vaziri, C., Tateishi, S., Yang, Y., Greenwalt, A. Function of Translesion DNA Polymerases in Genome Stability. (2015) Chapter 6, 91-126 
• Zlatanou, A., Sabbioneda, S., Miller, E.S., Greenwalt, A., Aggathanggelou A., Maurice, M.M., Lehmann, A.R., Stankovic, T., Reverdy C., Colland, F., Vaziri C., Stewart, G.S. (2015) USP7 is essential for maintaining Rad18 stability and DNA damage tolerance. Oncogene 
• Donohoe, D.R., Holley, D., Collins, L.B., Montgomery, S.A., Whitmore, A.C., Hillhouse, A., Curry, K.P., Renner, S.W., Greenwalt, A., Ryan, E.P., Godfrey, V., Heise, M.T., Threadgill, D.S., Han, A, Swenberg, JA, Threadgill, DW, Bultman SJ. (2014) A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner. Cancer Discov. 4(12): 1387-9 
• Yang, Y., Durando, M., Smith-Roe, S.L., Sproul, C., Greenwalt, A.M., Kaufmann, W., Oh, S., Hendrickson, E.A., Vaziri, C. (2013) Cell cycle stage-specific roles of Rad18 in tolerance and repair of oxidative DNA damage. Nucleic Acids Res. 1; 41(4): 2296-312

MEETINGS, ABSTRACTS, & POSTERS 

• Holk, A. 3D Printing Design and Application in Biomedical Research Training Miniseries (Parts I-IV) Lovelace Biomedical Research Institute 2021.
• Dallas Donohoe, Darcy Holley, Leonard Collins, Stephanie Montgomery, Alan Whitmore, Andrew Hillhouse, Kaitlin Curry, Sarah Renner, Alicia Greenwalt, Elizabeth Ryan, Deborah Threadgill, James Swenberg, David Threadgill, Scott Bultman. Abstract SY04-02: Dietary fiber protects against colorectal tumorigenesis in a microbiota-and butyrate-dependent manner. Cancer Research 2014
• Greenwalt, A., Korboukh,V., Hull-Ryde, E., Janzen, W., Vaziri, C. Polη-Dependent Translesion Synthesis: A Novel Target for Cancer Therapy Eukaryote DNA Replication & Genome Maintenance, Cold Spring Harbor Laboratories 2013 
• Greenwalt, A., Yang, Y., Durando, M., Yan, F., Sinnott, R., Mulvaney, K., Goldfarb, D., Whitehurst, A., Major, MB., Vaziri, C. A Novel Role for MageA4 in Cancer Genome Stability and DNA Damage Tolerance. Abstract for poster presentation. HHMI Translational Medicine Symposium. Chapel Hill, NC. 2013 
• Greenwalt, A., Hull-Ryde, E., Janzen, W., Vaziri, C. Rad18-Dependent Translesion Synthesis: A Novel Target for Cancer Therapy. Abstract for poster presentation. HHMI Translational Medicine Symposium. Chapel Hill, NC. 2012 
• Greenwalt, A., Davies, C., Tarran, R., What are the Effects of Cigarette Smoke on Airway Epithelial Cells? Abstract for poster presentation. University of North Carolina Biological and Biomedical Sciences Symposium. Chapel Hill, NC 2010. 
• Greenwalt, A., Saylor, W., Schmidt, C. Human Selection and Trait Evolution in the Chicken: A concentration on the developmental anatomy of the small intestine. Abstract for poster presentation. University of Delaware Undergraduate Research Symposium. Newark, DE